| Item Type | Name |
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Academic Article
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Inhibition of histone deacetylation enhances endotoxin-stimulated transcription but does not reverse endotoxin tolerance.
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Academic Article
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Lipopolysaccharide- and lipoteichoic acid-induced tolerance and cross-tolerance: distinct alterations in IL-1 receptor-associated kinase.
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Academic Article
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Association of an IL-1A 3'UTR polymorphism with end-stage renal disease and IL-1 alpha expression.
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Academic Article
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Distinct post-receptor alterations generate gene- and signal-selective adaptation and cross-adaptation of TLR4 and TLR2 in human leukocytes.
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Academic Article
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Endotoxin tolerance disrupts chromatin remodeling and NF-kappaB transactivation at the IL-1beta promoter.
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Academic Article
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Alpha2-adrenoceptor stimulation transforms immune responses in neuritis and blocks neuritis-induced pain.
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Academic Article
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Induction of RelB participates in endotoxin tolerance.
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Academic Article
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Assembly of inflammation-related genes for pathway-focused genetic analysis.
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Academic Article
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Toll-like receptor 4-dependent responses to lung injury in a murine model of pulmonary contusion.
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Academic Article
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G9a and HP1 couple histone and DNA methylation to TNFalpha transcription silencing during endotoxin tolerance.
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Academic Article
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RelB sustains IkappaBalpha expression during endotoxin tolerance.
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Academic Article
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Chromatin-specific remodeling by HMGB1 and linker histone H1 silences proinflammatory genes during endotoxin tolerance.
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Academic Article
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Pulmonary contusion primes systemic innate immunity responses.
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Academic Article
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The NF-kappaB factor RelB and histone H3 lysine methyltransferase G9a directly interact to generate epigenetic silencing in endotoxin tolerance.
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Academic Article
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Curcumin modulates leukocyte and platelet adhesion in murine sepsis.
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Academic Article
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Facultative heterochromatin formation at the IL-1 beta promoter in LPS tolerance and sepsis.
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Academic Article
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Aging does not reduce heat shock protein 70 in the absence of chronic insulin resistance.
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Academic Article
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NAD+-dependent sirtuin 1 and 6 proteins coordinate a switch from glucose to fatty acid oxidation during the acute inflammatory response.
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Academic Article
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Adoptive transfer of CD34(+) cells during murine sepsis rebalances macrophage lipopolysaccharide responses.
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Academic Article
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Regulation of IL-1 receptor-associated kinases by lipopolysaccharide.
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Academic Article
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The pathogenesis of pulmonary contusion: an open chest model in the rat.
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Academic Article
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Gene silencing in severe systemic inflammation.
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Academic Article
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Toll-like receptor 2 participates in the response to lung injury in a murine model of pulmonary contusion.
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Academic Article
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Endogenous signals released from necrotic cells augment inflammatory responses to bacterial endotoxin.
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Academic Article
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Epigenetic silencing of tumor necrosis factor alpha during endotoxin tolerance.
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Academic Article
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Dynamic and selective nucleosome repositioning during endotoxin tolerance.
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Academic Article
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NAD+-dependent SIRT1 deacetylase participates in epigenetic reprogramming during endotoxin tolerance.
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Academic Article
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MicroRNA-146a regulates both transcription silencing and translation disruption of TNF-a during TLR4-induced gene reprogramming.
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Academic Article
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Hematopoietic stem-progenitor cells restore immunoreactivity and improve survival in late sepsis.
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Concept
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Humans
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Concept
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CpG Islands
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Concept
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Hematopoietic Stem Cells
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Concept
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Sirtuin 1
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Concept
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Glucose Transporter Type 1
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Concept
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RNA Processing, Post-Transcriptional
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Concept
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Lymphocytes
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Concept
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Sirtuin 3
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Concept
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Receptor, Anaphylatoxin C5a
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Concept
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Weight Loss
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Concept
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Enzyme Stability
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Concept
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Atherosclerosis
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Concept
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Interleukin-1beta
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Concept
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Cerebrovascular Circulation
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Concept
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Response Elements
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Concept
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Antioxidants
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Concept
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Air Pollution
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Concept
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Oxidation-Reduction
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Concept
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Protein Stability
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Concept
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Stilbenes
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Concept
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Alzheimer Disease
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Concept
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Leukocytes, Mononuclear
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Concept
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Receptors, Interleukin-8B
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Concept
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Phagocytosis
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Concept
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Electrophoretic Mobility Shift Assay
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Concept
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Myeloid Progenitor Cells
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Concept
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Binding Sites
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Concept
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Antigens, CD34
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Concept
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Interleukin-8
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Concept
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Transcription Initiation Site
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Concept
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Chromatin Immunoprecipitation
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Concept
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Amino Acids
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Concept
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Blotting, Northern
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Concept
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Myeloid Differentiation Factor 88
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Concept
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Aged
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Concept
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African Continental Ancestry Group
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Concept
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Adenosine Triphosphate
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Concept
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Protein Biosynthesis
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Concept
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Methylation
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Concept
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Mice, Knockout
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Concept
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Cohort Studies
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Concept
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Antibodies
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Concept
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Oxidative Phosphorylation
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Concept
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Teichoic Acids
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Concept
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NF-kappa B p50 Subunit
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Concept
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STAT3 Transcription Factor
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Concept
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Blotting, Western
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Concept
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E-Selectin
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Concept
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Lipopolysaccharides
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Concept
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Thrombin
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Concept
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Chemokine CXCL2
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Concept
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Anti-Inflammatory Agents, Non-Steroidal
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Concept
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Dual Specificity Phosphatase 1
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Concept
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Endotoxins
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Concept
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Leukocyte Count
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Concept
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Obesity
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Concept
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Immunoprecipitation
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Concept
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Chromatin
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Concept
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Feedback, Physiological
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Concept
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Mice
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Concept
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Aging
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Concept
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Adaptation, Biological
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Concept
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Bone Marrow Cells
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Concept
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Cysteine
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Concept
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Chemokines, CC
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Concept
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Nucleosomes
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Concept
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Transcription, Genetic
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Concept
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Adiponectin
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Concept
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Adaptation, Physiological
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Concept
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Leukocytes
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Concept
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Tumor Necrosis Factor-alpha
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Concept
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Cecum
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Concept
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Dealkylation
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Concept
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Diabetes Mellitus, Type 2
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Concept
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CCAAT-Enhancer-Binding Protein-beta
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Concept
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Mice, Inbred C57BL
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Concept
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Regulatory Sequences, Nucleic Acid
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Concept
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Lysine
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Concept
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Enzyme Activation
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Concept
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Bronchoalveolar Lavage Fluid
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Concept
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T-Lymphocytes
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Concept
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Monocyte-Macrophage Precursor Cells
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Concept
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Calgranulin B
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Concept
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Antigens, CD
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Concept
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Signal Transduction
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Concept
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Monocytes
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Concept
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P-Selectin
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Concept
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Intestine, Small
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Concept
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Platelet Adhesiveness
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Concept
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Antigens, Ly
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Concept
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Enzyme-Linked Immunosorbent Assay
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Concept
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Protein Binding
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Concept
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Neutrophils
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Concept
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Intestinal Mucosa
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Concept
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DNA Methylation
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Concept
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Interleukin-10
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Concept
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Protein Transport
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Concept
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Necrosis
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Concept
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RNA, Small Interfering
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Concept
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Blood-Brain Barrier
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Concept
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Complement C5a
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Concept
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Cell Lineage
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Concept
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Adrenergic alpha-Agonists
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Concept
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Mitochondria
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Concept
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Flow Cytometry
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Concept
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Microscopy, Video
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Concept
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Aged, 80 and over
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Concept
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Circadian Rhythm
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Concept
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Cell Nucleus
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Concept
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Intercellular Adhesion Molecule-1
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Concept
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Air Pollutants
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Concept
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Mice, Inbred BALB C
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Concept
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Autophagy
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Concept
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Capillary Permeability
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Concept
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Mice, Obese
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Concept
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Myelopoiesis
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Concept
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Sirtuin 2
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Concept
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Sirtuins
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Concept
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Chemokines, CXC
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Concept
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Microcirculation
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Concept
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NAD
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Concept
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CD4-Positive T-Lymphocytes
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Concept
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3' Untranslated Regions
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Concept
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Rats
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Concept
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Sequence Homology, Amino Acid
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|
Concept
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Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating)
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Concept
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Rats, Wistar
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Concept
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Oligonucleotide Array Sequence Analysis
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Concept
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Middle Aged
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|
Concept
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Clonidine
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Concept
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Curcumin
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|
Concept
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Glycolysis
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Concept
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Rats, Sprague-Dawley
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Concept
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Heterochromatin
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Concept
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United States
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Concept
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Chemokine CXCL1
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Concept
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Cholesterol
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Concept
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MicroRNAs
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Concept
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Promoter Regions, Genetic
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Concept
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Base Sequence
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Concept
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Chromatin Assembly and Disassembly
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Concept
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Immunohistochemistry
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Concept
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Receptors, Adrenergic, alpha-2
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Concept
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Cell Line, Tumor
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Concept
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Carbazoles
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Concept
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Hypoxia-Inducible Factor 1, alpha Subunit
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Concept
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Carbohydrate Metabolism
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Concept
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RNA-Binding Proteins
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Concept
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Polysaccharides, Bacterial
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Concept
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Phosphorylation
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Concept
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Ribosomes
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Academic Article
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Mitogen-activated protein kinase phosphatase 1 disrupts proinflammatory protein synthesis in endotoxin-adapted monocytes.
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Academic Article
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MicroRNA-146a and RBM4 form a negative feed-forward loop that disrupts cytokine mRNA translation following TLR4 responses in human THP-1 monocytes.
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Academic Article
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Deacetylation by SIRT1 Reprograms Inflammation and Cancer.
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Academic Article
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Methylomics of gene expression in human monocytes.
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Academic Article
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MicroRNA 21 (miR-21) and miR-181b couple with NFI-A to generate myeloid-derived suppressor cells and promote immunosuppression in late sepsis.
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Academic Article
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Epigenetic coordination of acute systemic inflammation: potential therapeutic targets.
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Academic Article
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Age-related variations in the methylome associated with gene expression in human monocytes and T cells.
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Academic Article
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SIRT1 mediates a primed response to immune challenge after traumatic lung injury.
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Academic Article
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Transcriptomic profiles of aging in purified human immune cells.
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Academic Article
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Resveratrol attenuates microvascular inflammation in sepsis via SIRT-1-Induced modulation of adhesion molecules in ob/ob mice.
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Academic Article
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Alterations of a Cellular Cholesterol Metabolism Network Are a Molecular Feature of Obesity-Related Type 2 Diabetes and Cardiovascular Disease.
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Academic Article
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NFI-A disrupts myeloid cell differentiation and maturation in septic mice.
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Academic Article
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GAPDH Binding to TNF-a mRNA Contributes to Posttranscriptional Repression in Monocytes: A Novel Mechanism of Communication between Inflammation and Metabolism.
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Academic Article
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Sirtuin-2 Regulates Sepsis Inflammation in ob/ob Mice.
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Academic Article
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Stat3 and C/EBPß synergize to induce miR-21 and miR-181b expression during sepsis.
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Academic Article
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Adiponectin treatment attenuates inflammatory response during early sepsis in obese mice.
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Academic Article
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Long-term outdoor air pollution and DNA methylation in circulating monocytes: results from the Multi-Ethnic Study of Atherosclerosis (MESA).
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Academic Article
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Correction: Sirtuin-2 Regulates Sepsis Inflammation in ob/ob Mice.
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Grant
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Epigenetics of Severe Systemic Inflammation
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Grant
|
Epigenetics of Severe Systemic Inflammation
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Grant
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FUNCTIONAL AND METABOLIC PROPERTIES OF TOXIC NEUTROPHILS
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Grant
|
Function and Metabolic Properties of Toxic Neutrophils
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Academic Article
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Frontline Science: Myeloid cell-specific deletion of Cebpb decreases sepsis-induced immunosuppression in mice.
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Academic Article
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Transcriptomic profiles of aging in naïve and memory CD4+ cells from mice.
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Academic Article
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The Oxidative State of Cysteine Thiol 144 Regulates the SIRT6 Glucose Homeostat.
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Academic Article
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Expression of C/EBPß in myeloid progenitors during sepsis promotes immunosuppression.
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Academic Article
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Pyruvate dehydrogenase complex stimulation promotes immunometabolic homeostasis and sepsis survival.
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Academic Article
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IL-10 induces an immune repressor pathway in sepsis by promoting S100A9 nuclear localization and MDSC development.
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Academic Article
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Intracellular S100A9 Promotes Myeloid-Derived Suppressor Cells during Late Sepsis.
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Academic Article
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Sirtuins and Immuno-Metabolism of Sepsis.
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Academic Article
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Frontline Science: Monocytes sequentially rewire metabolism and bioenergetics during an acute inflammatory response.
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Academic Article
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SIRT1 Mediates Septic Cardiomyopathy in a Murine Model of Polymicrobial Sepsis.
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Academic Article
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Cysteine thiol oxidation on SIRT2 regulates inflammation in obese mice with sepsis.
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Academic Article
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S100A9 maintains myeloid-derived suppressor cells in chronic sepsis by inducing miR-21 and miR-181b.
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